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Rhbdd3, a member of the rhomboid protease family, negatively regulates DC activation and maintains the balance of Treg and Th17 cells by inhibiting IL-6 production in DCs, thus contributing to the prevention of autoimmune diseases [97]
By integrating metagenomic profiles, we further revealed that gut microbial dysbiosis in RBD-PD and iRBD drives a functional shift away from dietary fiber fermentation and toward enhanced degradation of protein, aromatic amino acids, glycine, and intestinal mucin glycans
Disclosure of interest: All authors: nothing to disclose E-Posters - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.01 - REHABILITATION P2213 - ESOC25-667 BARRIERS TO ACCESSING AND PROVIDING EXERCISE REHABILITATION FROM THE PERSPECTIVE OF STROKE SURVIVORS AND LEISURE CENTRE INSTRUCTORS Lucy Watson 1 , Esmee Thrasher 1 , Hannah Jarvis 1 1 Lancaster University, Lancaster, United Kingdom Background and Aims: Exercise rehabilitation after a stroke is vital to improve physical and psychological well-being, but stroke survivors experience an array of barriers preventing participation
10.1073/pnas.0636904100