PMID: 29222629 Li Z, Zheng Z, He W, et al
The At APX4 and At APX6 (APX-L and APX-R) proteins lack essential catalytic residues, ASC-binding sites, and haem-binding sites (Granlund et al
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Nutrients 15(4):847 Markus CR et al (2000) The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress
If our hypothesis is confirmed (i.e., some of these host cleavage sites prove to be functional), that leaves us with an interesting questionwhat evolutionary advantages are driving some viruses to go so far as to degrade or block the synthesis of GSH and specific host selenoproteins