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Numerous data indicate the importance of GSH and the GSH/GSSG ratio in the regulation of tumor cell viability, in the initiation of tumor development, progression, and drug resistance

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There is no good quality clinical evidence to suggest that a diagnosis of Gilberts syndrome puts patients at risk of toxicity at therapeutic doses of paracetamol, and the assertion that patients are at greater risk of toxicity following overdose remains theoretical (see Fig

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