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(2) Emulsion-evaporation method in which PLGA and agents to be encapsulated are dissolved in a volatile water-immiscible organic solvent, which is emulsified into aqueous external phase followed by evaporation of the organic solvent to form PLGA nanoparticles

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Finally, we discuss the current limitations of these platforms and outline the major challenges that must be addressed to advance their translational potential

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10.1016/s0168-9525(03)00115-x 30 ChandraD.JahangirA.CornelisF.RombautsK.MeheusL.JorcykC