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Sulfur dioxide (SO), a byproduct of fossil fuel combustion, remains a significant air pollutant, contributing to acid rain and respiratory diseases

Both doses are increased gradually over several weeks to improve tolerability

In a study of prostate cancer, SFN did not reduce the cytotoxic effects of drugs but, rather, strongly increased their anticancer efficacy against prostate cancer stem cells

Generally, ensuring solubilization and preventing misfolding is a primary event of HSP70 activity, whereas the ubiquitinproteasome system (UPS) is a compensatory mechanism to degrade proteins that are irreversibly damaged or become damaged at excessive levels unable to be refolded