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Additionally, NRC-03 and NRC-07, two AMPs from the pleurocidins AMP family, exhibited equal killing effect at a concentration of 50M on normal MCF7 cells and on paclitaxel-resistant breast cancer cell line MCF7-TX400 that possess 2.6 times of P-gp expression more than the normal MCF7 cells, achieving about 60% of cell killing rate
They are not identical copies of amylin, and they do not share the same receptor selectivity, molecular engineering, clinical database, or stage of development
What the animal data cannot tell us is what happens in humans
Cons: Few skin whitening procedures may cause pain or discomfort in some people
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: implications for the response to hormonal therapy
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