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Women of childbearing age should use contraception while on tirzepatide and discontinue the medication at least 2 months before attempting conception to allow complete washout given the long half-life

Single-stranded DNA antibodies have also been identified (505), along with anti-ganglioside antibodies (508), autoantibodies against endothelial and neuronal cells (506), and phospholipid autoantibodies (506, 508, 509)

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If these findings translate successfully into clinical trials, such drugs could help improve core symptoms of autism, especially in cases with underlying neural circuit dysfunction

Retatrutide has produced weight loss results that far exceed those of semaglutide (Ozempic), reducing weight by up to 24% in 48 weeks, compared to semaglutides 17.4% reduction after 68 weeks