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The BBB is a cellular structure formed by the neurovascular unit (NVU) and is organized by a monolayer of endothelial and mural cells

The solution prepaed in setp 1

Vials (50 mg each, subcutaneous route only) One 50 mg vial lasts about 10 to 20 days at 2.5 to 5 mg per day

Cai et al., 2014)

Conen, D, Ke Wang, M, Popova, E, Chan, MT, Landoni, G, Cata, JP, Reimer, C, McLean, SR, Srinathan, S, Reyes, JT, Grande, AM, Tallada, AG, Sessler, DI, Fleischmann, E, Kabon, B, Voltolini, L, Cruz, P, Maziak, D, Gutirrez-Soriano, L, McIntyre, WF, Tandon, V, Martnez-Tllez, E, Guerra-Londono, JJ, DuMerton, D, Wong, RH, McGuire, AL, Kidane, B, Roux, DP, Shargall, Y, Wells, JR, Ofori, SN, Vincent, J, Xu, L, Li, Z, Eikelboom, JW, Jolly, SS, Healey, JS, Devereaux, PJ, Wang, MK, Wells, JR, Healey, JS, McIntyre, WF, Sessler, DI, Rajaram, R, Vaporciyan, AA, Mehran, RJ, Sepesi, B, Walsh, GL, Rice, DC , Swisher, SG