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Arch Womens Ment Health 17 , 8795, (2014)

While magnesium and amitriptyline each improved many of the assessed parameters, the combination of the two was more effective than either alone and significantly improved pain, tender points, depression, anxiety, sleep, and irritability

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Naturally aged mice exhibited significantly lower sperm concentration and motility compared to young mice , confirming age-related declines in sperm quality