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They are not subject to the same rigorous pre-market safety and efficacy testing as licensed medicines

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Funding Statement The author(s) declare that financial support was received for the research and/or publication of this article

Studies with PYY agonists administered intravenously have shown reduction in food intake with increased satiety [92, 93], however, a nasal PYY agonist showed minimal efficacy with poor tolerability [94]