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It reduces how much energy comes in by suppressing appetite, slowing digestion, and improving how the body handles the food that does get consumed

The phosphorylated analogue P-DSIP has been reported to produce larger increases in slow-wave and paradoxical sleep than the parent peptide in unrestrained rats under continuous nocturnal infusion (Yehuda & Mostofsky, 1989)

However, degradation still progresses over time

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Since the mode of action of both the peptides appears to be different, they may complement each other when presented together and thereby provide a potentially greater growth hormone response