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Figure 3: Chemical structures of Nle1-AngIV (Nle-Tyr-Ile-His-Pro-Phe) and Dihexa (N-hexanoic-Tyr-Ile-(6) amino hexanoic amide)

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In this context, the practical indicative evidence may be even more important

Park J, Lee H, Lee S, Lee H (2022) Interventions on reducing exposure to endocrine disrupting chemicals in human health care context: a scoping review

The AMPK-mediated response mitigates mitochondrial stress, promotes mitochondrial biogenesis, facilitates mitophagic clearance of irreversibly damaged mitochondria, enhances glucose uptake, and supports anaerobic glycolysis as an alternative ATP source [200,201,202,203,204]