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While a substantial amount of preclinical data has been published, human evidence for efficacy and safety remains limited, which is why BPC-157 is currently not approved for human consumption

Instead, the brand opts for innovative formulations that may truly make a difference

Interestingly, ATX inhibition leads to increased extracellular LPA levels, suggesting ATX may regulate LPA-receptor interactions through LPA chaperone functions beyond enzymatic activityproviding new mechanistic insights for ATX inhibitor efficacy (81)

Reviewer: [to be signed off by BadHunga before publish] About the author Sebastian Reuters is a science and health writer working with BioHack London on research-orientation content

doi: 10.1093/EURHEARTJ/EHR304 94 RoutsiCStanopoulosIZakynthinosEPolitisPPapasVZervakisDet al