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Nuclear factor erythroid 2-related factor 2 (Nrf2) functions as a transcription factor and a central regulator of the bodys oxidative stress response 11,12 , so that activating Nrf2 holds promise as an effective therapeutic strategy in OA

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Tukhovskaya et al

These effects appear to be independent of thyroid hormone levels, reinforcing the idea that the inflamed thyroid gland may itself contribute to symptom persistence via immune-mediated mechanisms

The withdrawal of whole blood is permitted for the purpose of separating and locally re-inject platelet-rich plasma