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By suppressing this inflammatory chemokine network, resveratrol reduces leukocyte recruitment, limits macrophage polarization toward the pro-inflammatory M1 phenotype, and restores immune balance, thereby interrupting the chronic inflammatory environment that promotes EMs lesion establishment and progression ( In vivo , resveratrol treatment in EMs rodent models produces a strong and dose-dependent increase in systemic and tissue antioxidant capacity
Replenishes nutritional deficiencies in the body
Au-del de cette action directe, le glutathion rgnre les vitamines C et E une fois oxydes, prolongeant leur activit antioxydante
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For innate immune responses to viruses it is important to note that the most common mutation (R47H) in the microglial phagocytic triggering receptor expressed on myeloid cell 2 (TREM2) is a strong risk factor for AD and is characterized by an enhanced type 1 IFN response (Korvatska et al., 2020
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