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It supports the nervous system, which can positively impact mood and emotional balance

Additionally, data from a Phase I clinical trial (NCT02861300) indicated that the combination of CB-839 and capecitabine which is a prodrug of 5-FU, was well tolerated by CRC patients at bioactive doses

10.1016/j.toxicon.2022.106996 190 MaekA.KocotJ.MitrowskaK.PosyniakA.KurzepaJ

This multi-target approach contrasts with the single-target strategy commonly used in modern drug development, which often encounters issues such as drug tolerance and side effects

(But again, these are animal studies, so theres no evidence that the benefits would translate to humans.) Glycine also has an impact on the nervous system, which may help with calming down the body and leading to deeper REM sleep