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Obesity and the gut microbiome: Striving for causality (in Eng)

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If risk factors exist, professional assessment helps decide whether testing is appropriate

Among the three precursor amino acids, cysteine proves to be the rate-limiting factor for GSH synthesis since its intracellular availability is lower than the Km value of -glutamyl cysteine synthase (GCS), whereas glutamate and glycine are abundant in the cell [7, 70]

Procyanidin oligomers and polymers reach the large intestine where they are subjected to microbial metabolism yielding e.g., phenylvalerolactones (see section 6.1 Pre-systemic metabolism: role of gut microbiota)