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The calculated stability l \ n based on single phase exponential decay for Norleual was 4.6 min and for D-Nle-Tyr-Ile-NH-(CH 2 )5-CONH 2 stability t 1/2 was 79.97 min

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In some embodiments, the use of an appropriate thermosetting polymer and an appropriate copolymer (e.g., a gelling agent) in combination with a specific pH range for the formulation allows for high temperature sterilization of formulations described with substantially no degradation of the therapeutic agent or the polymeric excipients

10.3390/pharmaceutics14091890 89 QinY.GeG.YangP.WangL.QiaoY.PanG.et al (2023)

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