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This process begins with endothelial dysfunction, a critical event in the pathogenesis of atherosclerosis [64]

However, some challenging biological in vitro hurdles remain unresolved i.e., enhancing biocompatibility, stability, and biodegradability, assuring nontoxicity, timely turns on and off

Melanin is what makes the skin colour, and in case of excess production or unevenness, dark spots and pigmentation would be observed

It seems that its pharmacological properties are more suitable for clinical use compared to GKT136901 ( ML171 showed the most selective NOX-1 inhibition out of 16,000 other phenothiazines tested in a structural relationship study at the Scripps Research Institute

10.1016/j.carbpol.2019.115419 187 TalukderM