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Lycopene alleviates age-related cognitive deficit via activating liver-brain fibroblast growth factor-21 signalling

Pereira S, Fontes F, Sonin T, Dias T, Fragoso M, Castro-Lopes JM, et al Chemotherapy-induced peripheral neuropathy after neoadjuvant or adjuvant treatment of breast cancer: a prospective cohort study Support Care Cancer

For more pronounced changes, such as significant skin brightening and the fading of hyperpigmentation, consistent treatment over three to six months is often required