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Description

Although it occurs naturally within the body, glutathione levels can decline by several factors that include poor nutrition, environmental toxins, stress, and even age

Consequently, many GSH-responsive nanoplatforms are designed either to deplete GSH by targeting these pathways or to exploit high GSH levels as triggers for selective drug release

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PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin

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