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It upregulates the expression of vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and their respective receptors at sites of injury, directly promoting angiogenesis and epithelial repair

This is especially important for women and anyone over 40, populations where muscle preservation during weight loss is critical for long-term metabolic health

Research publications have found that SARMs can suppress natural testosterone (though usually temporarily), affect cholesterol levels, and elevate liver enzymes

Discontinue use if irritation, redness or allergic reactions occur

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers