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It also modulates PDHA1 and PI3K-Akt-mTOR signaling to promote lipid metabolism disorders and PDE3B (promoting cAMP-mediated lipolysis)

As of the current literature, published peer-reviewed studies have primarily utilized the unmodified AEDG peptide (Epithalon) or the parent extract epithalamin

The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution

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