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Melanocyte activation mechanisms and rational therapeutic treatments of solar lentigos

Homeostatic regulation of GSH levels Glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), and glucose-6-phosphate dehydrogenase (G6PD) are responsible for recycling of oxidized glutathione (GSSG) back to reduced glutathione (GSH)

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Further, the sensitive coordinate bond of catechol-Fe and dynamic Schiff base bonds improved the mechanical properties of the hydrogel as well as their injectability and self-healing properties, thus making the adhesive hydrogel a smart wound sealant to heal infected wounds and improve tissue regeneration in vivo