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As many of these transmembrane receptors are dimerized or heterodimerized by the interaction with cognate ligands to activate signalling pathways 1,38 , the methodology reported here is applicable to the design and synthesis of such artificial agonists

Phase separation due to reduced solubility can occur under certain conditions of shipping or storage (e.g

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Collagen, the primary structural protein in ligaments, consists of triple helices that form robust fibrils through intermolecular cross-linking