Coniferyl ferulate is a potent inhibitor of glutathione S-transferase ( GST ) ( IC = 0.3 M), which downregulates 50 P-gp expression, induces apoptosis in B-MD-C1 (ADR+/+) cells, and reverses multidrug resistance
Summary Keywords blood-brain barrier dysfunction, diagnostic imaging, magnetic resonance imaging, neurodegeneration, positron emission tomography Citation Moyaert P, Padrela BE, Morgan CA, Petr J, Versijpt J, Barkhof F, Jurkiewicz MT, Shao X, Oyeniran O, Manson T, Wang DJJ, Gnther M, Achten E, Mutsaerts HJMM and Anazodo UC (2023) Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective
Thanks to the magnetic cores, external low-power radiofrequency field could facilitate deep penetration of drugs across bloodbrain tumor interface
Badrasawi, M
Mol Aspects Med 30:1328 Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL (2009b) Glutathione dysregulation and the etiology and progression of human diseases