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The authors reported an increased Firmicutes/Bacteroidetes ratio and Streptococcus abundance, with a reduction in Prevotella strains in patients with active MS when compared with healthy controls and patients with MS in remission ( Prevotella strains was inversely associated with Th17 cells in the small intestine, while positively related to disease activity ( 2.4.3 Treatment strategies 2.4.3.1 Probiotics Synergistic therapeutic effects may be exerted by the different strains in probiotic cocktails

[DOI] [PubMed] [Google Scholar] 498.Porcelli A.M., Angelin A., Ghelli A., Mariani E., Martinuzzi A., Carelli V., et al

10.1038/mp.2016.50 383 RohJ

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The reactivity of these species means that their accumulation must be controlled, but also that they are excellent signaling molecules that underpin plant development and responses to the environment (Considine and Foyer, 2014