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The SCFA-producing species, including Faecalibacterium prausnitzii , Bacteroides spp., and Clostridium spp., are well-known bacterial genera for synthesizing butyrate, which plays a vital role in maintaining intestinal barrier integrity and decreasing inflammation

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Risk factors include occupations requiring prolonged standing, being overweight, having flat feet or high arches, tight calf muscles, and sudden increases in physical activity