This multi-target mechanism explains why it has documented effects on skin, hair, wounds, lungs, and even cancer gene regulation something that would be puzzling if it only had one mechanism
& Zhou, G
Thymosin beta-4 peptides have been examined for their effects on inflammatory signaling networks and cellular survival pathways, with studies describing modulation of endothelial behavior, oxidative stress responses, and reparative cell activity in experimental models [7][8]
This response was significantly different from the background response which was obtained by applying Glu in the presence of glutamate receptor blockers, namely, AP5 25 M, a broad-spectrum NMDAr antagonist, DNQX 10 M, a non-NMDA receptor antagonist, and MPEP 10 M, a type 5 metabotropic glutamate receptor antagonist
Any serotonergic medications, drugs, or herbals like St Johns Wort taken together, can be especially risky especially in high quantities or for long durations of time