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A method for preventing drug-induced ototoxicity in an individual in need thereof comprising intratympanic administration of a pharmaceutical composition comprising a therapeutic agent selected from a JNK inhibitor, a TRPV modulator, a MET channel inhibitor, and an otoprotectant to the individual in need thereof, wherein the pharmaceutical composition is administered prior to onset of therapy with the drug, and wherein the composition provides sustained release of the therapeutic agent into the ear for a period of at least 5 days after a single administration

Albumin is a reliable drug-delivering molecule: Highlighting points in cancer therapy

For first responders, the combination of chronic stress, shift work sleep disruption, and physical demands can accelerate testosterone declineoften 10-15 years earlier than civilian counterparts

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