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This observation, combined with evidence that older adults have blunted MOTS-c responses to exercise, supports the hypothesis that declining mitochondrial peptide signaling contributes to the reduced exercise adaptability seen in aging

Researchers must use aseptic technique, sterile gloves, syringes and vials to prevent contamination and preserve substance integrity throughout experimental procedures

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However, true candidacy is deeply personal and is determined through a comprehensive medical evaluation, not a simple checklist