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La ricerca dagli anni 90 (gruppo Sikiric, Zagabria) mostra in modelli animali effetti su cicatrizzazione dei tendini, mucosa intestinale, angiogenesi e sistema nervoso

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Second, the development of new drugs requires additional and more detailed preclinical and clinical studies to determine whether long-term use is biotoxic, whether the drug has adverse effects on other peripheral organs or whether the drug candidate has a real therapeutic effect on the patients