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The appearance of mild-yellowish, mosaic symptoms was associated with a dramatic, 20-fold induction of defense-related genes like PR-1, chitinase and GST (Niehl et al., Potato virus Y (PVY) strains, the aggressive PVY NTN and the mild PVY N (Kogovsek et al., NTN -inoculated leaves displayed chlorotic and/or necrotic ringspot type lesions, while PVY N caused a mild chlorotic ringspot

131 , e142428 (2021)

It upregulates peroxisome proliferator-activated receptor gamma coactivator 1 alpha, the master regulator of mitochondrial biogenesis, which in turn stimulates mitochondrial proliferation [138]

PMID 12369887

Research Snapshot HGF/c-Met Pathway: Dihexa is primarily investigated for its ability to potentiate Hepatocyte Growth Factor (HGF) signaling through the c-Met receptor, a pathway involved in neuronal survival, synapse formation, and dendritic spine growth