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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

Combination therapy (endogenous support + exogenous supplementation/topicals) is often most effective

Gold-Nanopartikel mit GHK-Cu-Beschichtung zeigten in praeklinischen Studien eine verbesserte Wundheilung und reduzierte Entzuendung im Vergleich zu freiem GHK-Cu

10.1111/jcmm.70691 Summary Keywords chondrocyte, extracellular matrix, ferroptosis, GPX4, osteoarthritis Citation Zhang L, Li J, Yang X and Yang L (2026) Glutathione peroxidase 4 as an emerging therapeutic target in osteoarthritis: focus on ferroptosis