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Common experimental arenas include: Telomere and cellular aging models: Evaluation of telomerase activity, telomere length dynamics, replicative lifespan, and senescence markers in cell culture and animal studies

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Gut microorganisms can impact central nervous system processes through immune system modulation and communication via the vagus nerve [54]

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Otic agents and/or other pharmaceutical agents disclosed herein are optionally incorporated within controlled release particles, lipid complexes, liposomes, nanoparticles, microspheres, nanocapsules or other agents which enhance or facilitate the localized delivery of the otic agent