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JAK-STAT signaling: from interferons to cytokines

It's a sharp, radiating, life-altering event that can bring your world to a screeching halt

Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial

That's a good question because I think this would tell us, are we just like with sort of how long maternity leave type things

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