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doi: 10.3389/fmed.2025.1633447 Received 22 May 2025 Accepted 11 August 2025 Published 29 August 2025 Volume 12 - 2025 Edited by Zili Xie, Icahn School of Medicine at Mount Sinai, United States Reviewed by Nina Fuller-Shavel, Synthesis Clinic, United Kingdom Ali Mussa, Omdurman Islamic University, Sudan Xiaoqing Cathy Cheng, Washington University in St

Mice undergoing in vivo reprogramming were found to become depleted in B 12 and show signs of methionine starvation while supplementing reprogramming mice and cells with B 12 increased reprogramming efficiency, indicating a cell-intrinsic effect

For people with diabetes, rapid improvement in blood glucose control may occasionally be associated with transient worsening of diabetic retinopathy