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In STEP 1, semaglutide 2.4 mg produced a mean body-weight reduction of approximately 14.9% over 68 weeks

When neurological symptoms are present, more intensive treatment is required: 1 mg hydroxocobalamin on alternate days until no further improvement occurs, followed by maintenance therapy every two months

Furthermore, kidney infections can sometimes lead to more serious conditions, such as sepsis, if bacteria enter the bloodstream