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Glycine betaine and proline betaine in human blood and urine

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On the other hand, activation of the SNS in turn activates peripheral leukocytes to promote expression of NF-B-mediated pro-inflammatory immune response genes such as IL-1, IL-6, and TNF- via adrenaline and noradrenaline, which may generate an inflammatory environment in the periphery (Grebe et al., 2010)