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[] CONCLUSION While a multitude of observational and experimental studies have examined environmental risk factors in CKDu, no single causative factor or pathomechanism has been designated so far

Nanoscale 4 , 29462957 (2012)

Mol Biol Rep 40(2):12011210

In mice, aneuploidy increased from approximately 15% to 43% with age, but SIRT2 overexpression lowered spindle defects and misalignment and increased pregnancy rates from 25% to 75% in transgenic females