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As pointed out [60], it has to be the counteraction of the reduced capillary perfusion pressure, increased cerebral blood volume, venous flow obstruction, increased intracranial pressure and blood-brain barrier disruption, resulting in a decreased cerebral blood flow [60]

Eczema is a chronic condition with natural fluctuations, and shorter periods cannot distinguish treatment effects from random variation

~80 ng/mL by age 60 (60% decline) CLINICAL PROGRAMS NCT05239615 (topical for photoaging, Phase II, completed 2024)

If no, go to step iii

By controlling inflammation, it reduces excessive scar tissue (fibrosis) formation, allowing muscles and tendons to regain their original flexibility and tensile strength (Mcauley-November, 2025)