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A mortality study on male subjects exposed to polyfluoroalkyl acids with high internal dose of perfluorooctanoic acid

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We might adjust the dosage for elderly patients based on their health and medications

Unexpectedly, activation of p21, ICAM1, or SRXN1 was not observed (Supplementary Figure S5), although DNA ( Figure 6 ) is consistent with the lack of activation of an adaptive oxidative stress response pathway observed here and in a previous study ( Figure 7 , AQ-QI and DEAQ-QI exposure resulted in activation of the ER stress response