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Han L, Zhang Q, Shi C, Cavazos A, Ruvolo VR, Leverson JD, Dail M, PhillipsDC, Chen J, Jin SS, Jacamo R, Daver N, Jabbour E, Kantarjian HM, Andreeff M , SampathD, Konopleva M

Chloramphenicol eye ointment is one of the established topical options used in the UK for this purpose

However, it may have other activities

The peptide activates vascular endothelial growth factor receptor 2 (VEGFR2), triggering the VEGFR2-Akt-eNOS pathway, which promotes angiogenesis and improves blood flow to damaged tissue

Such heterogeneity influences how therapeutics enter tumor tissue, move through the interstitium, remain locally available, engage immune and stromal components and generate durable responses