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Conclusion Both the central circadian clock system and the control center of the GH/IGF-1 axis are located in the hypothalamus and related genes/hormones are expressed/released in circadian rhythm, which regulate metabolism through multi-level interactions
Rather than continuous supplementation, Epitalon aims to stimulate the pineal gland restoration processes that then continue independently for months
Statistical analysis The data are shown as the mean and standard deviation
Rising haemoglobin and normalisation of mean cell volume usually become evident within one to two weeks, with full blood count (FBC) monitoring recommended after approximately 2 weeks and again after 810 weeks to confirm response
The analysis was done after the fact rather than as a primary endpoint, and the clocks were measured in blood, so they track systemic aging rather than the brain in particular
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