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Activated MEK1/2 then activates ERK1/2 (MAPK)

Integrin signaling through elevated integrin 1 and 1 expression mediates cell adhesion to extracellular matrix, cell migration and proliferation, growth factor secretion, and cytoskeleton organization

The science is biologically plausible, the early findings are encouraging, and the available safety data appears favorable, but its important to be transparent about what we know, what we dont know, and where the evidence still needs to mature

Researchers should document all preparation procedures according to laboratory recordkeeping requirements