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Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection
virtually all gray matter areas can be involved including cerebral cortex, hippocampus, deep gray matter nuclei, cerebellum and even spinal gray matter (Calabrese et al., 2015
This has far-reaching effects, from maintaining healthy skin to supporting sharp cognitive function