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While many get enough from a balanced diet, certain groups of people may need supplementation, including those following plant-based diets, individuals over 50 or people with specific medical conditions

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Specific dosing parameters vary significantly between studies and animal models researchers should reference the primary literature for protocol design

Common side effects associated with B12 supplementation include: Local injection site reactions (for intramuscular preparations): Pain, redness, or swelling at the injection site Mild bruising or tenderness Itching localised to the injection area These reactions are usually self-limiting and resolve within 2448 hours

The amount of vitamin B12 your body needs depends on your age