In some embodiments, the otic formulations or compositions disclosed herein comprise poloxamer 407
Quantitation of peptides was performed with PEAKS Studio XPro search engine, selected Label Free Quantification under the Quantifications options using 20 ppm for mass error tolerance and 3 min for retention time shift tolerance (Clement et al, 2018)
Physiol Rev 100(1):171210 Cao S, Zhang Q, Wang C, Wu H, Jiao L, Hong Q et al (2018) LPS challenge increased intestinal permeability, disrupted mitochondrial function and triggered mitophagy of piglets
Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling
rifampin, St John's wort ) drugs that inhibit P-glycoprotein or P-450 (e.g