Furthermore, NGF and its receptors are expressed, and in many cases, modulated during stress in non-neural tissues, such as epithelial cells, fibroblasts, lymphocytes, activated macrophages, the pancreas, the heart and the liver (Yamamoto et al., 1996
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doi: 10.1371/journal.pone.0005692 48 AllenJEMaizelsRM
Therefore, reducing neuronal death is crucial for the treatment of secondary TBI
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