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Quercetin treatment also attenuates renal TEC senescence by promoting mitophagy ( 3.3.2 Nrf2 activators The activation of Nrf2-ARE signaling pathway also plays an important role in protecting against mitochondrial dysfunction through promoting mitophagy (Xiao et al., 2017

Redox Biol 24:101218 Torresano L, Nuevo-Tapioles C, Santacatterina F, Cuezva JM (2020) Metabolic reprogramming and disease progression in cancer patients

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To this end, we evaluated multiple cellular parameters including loss of cell viability, caspase 3 activation, GSH-conjugate formation, GSH homeostasis, and cellular stress response pathway activation in mock- and GSTP1 -transfected HepG2 cells